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Panoply™ Human PLEC Knockdown Stable Cell Line

Cat.No.
CSC-DC011918
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PLEC1
Synonyms
HD1; PCN; EBS1; EBSO; PLTN; PLEC1; LGMD2Q; PLEC1b
Gene Description
plectin 1, intermediate filament binding protein 500kDa
Gene ID
UniProt ID
Q15149
mRNA Refseq
Protein Refseq
Chromosome Location
8q24
Function
actin binding; ankyrin binding; protein binding; structural constituent of muscle; structural constituent of muscle;
Pathway
Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic execution phase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem;
MIM

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