Panoply™ Human PLCB1 Knockdown Stable Cell Line

Name: Panoply™ Human PLCB1 Knockdown Stable Cell Line
SKU: CSC-DC011895
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC011895

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC011895
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	PLCB1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) [ Homo sapiens ]
Gene Symbol	PLCB1
Synonyms	PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154
Gene Description	phospholipase C, beta 1 (phosphoinositide-specific)
Gene ID	23236
Uni Prot ID	Q9NQ66
m RNA Refseq	NM_182734.1
Protein Refseq	NP_877398.1
Chromosome Location	20p12
Function	GTPase activator activity; calcium ion binding; calmodulin binding; enzyme binding; lamin binding; phosphatidylinositol phospholipase C activity; phosphatidylinositol phospholipase C activity; phosphatidylinositol-4,5-bisphosphate binding; protein homodimerization activity; signal transducer activity;
Pathway	AMPK signaling, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem;
MIM	607120

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