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Panoply™ Human PKLR Knockdown Stable Cell Line

Cat.No.
CSC-DC011847
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PKLR
Synonyms
PKLR; pyruvate kinase, liver and RBC; pyruvate kinase isozymes R/L; pyruvate kinase 1; pyruvate kinase type L; pyruvate kinase isozyme R/L; R-type/L-type pyruvate kinase; red cell/liver pyruvate kinase; pyruvate kinase, liver and blood cell; PK1; PKL; PKR; RPK; PKRL;
Gene ID
UniProt ID
P30613
mRNA Refseq
BC025737
Chromosome Location
1q22
Function
ATP binding; magnesium ion binding; nucleotide binding; potassium ion binding; pyruvate kinase activity; transferase activity;
Pathway
ChREBP activates metabolic gene expression, organism-specific biosystem; Developmental Biology, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Glucose metabolism, organism-specific biosystem; Glycolysis, organism-specific biosystem; Glycolysis / Gluconeogenesis, organism-specific biosystem; Glycolysis / Gluconeogenesis, conserved biosystem;
MIM

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