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Panoply™ Human PAN2 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC011274

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC011274
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene PAN2
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name PAN2 PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) [ Homo sapiens ]
Gene Symbol PAN2
Synonyms PAN2; PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae); ubiquitin specific peptidase 52 , ubiquitin specific protease 52 , USP52; PAB-dependent poly(A)-specific ribonuclease subunit 2; hPAN2; KIAA0710; PAN2 homolog; PABP1 dependent poly A specific ribonuclease subunit (S. cerevisiae); ubiquitin specific protease 52; ubiquitin specific peptidase 52; PABP-dependent poly(A) nuclease 2; PAN2 polyA specific ribonuclease subunit; inactive ubiquitin carboxyl-terminal hydrolase 52; USP52; FLJ39360;
GeneID 9924
Uni ProtID Q504Q3
mRNA Refseq BC024043
Chromosome Location 12q13.2
Function exonuclease activity; hydrolase activity; nucleic acid binding; poly(A)-specific ribonuclease activity; ubiquitin thiolesterase activity;
Pathway Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem;
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