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Panoply™ Human PAICS Knockdown Stable Cell Line

Cat.No.
CSC-DC011256
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
PAICS
Synonyms
ADE2; AIRC; PAIS; ADE2H1
Gene Description
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
Gene ID
UniProt ID
P22234
mRNA Refseq
Protein Refseq
Chromosome Location
4q12
Function
5-(carboxyamino)imidazole ribonucleotide mutase activity; ATP binding; identical protein binding; phosphoribosylaminoimidazole carboxylase activity; phosphoribosylaminoimidazolesuccinocarboxamide synthase activity; protein binding;
Pathway
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, organism-specific biosystem; Inosine monophosphate biosynthesis, PRPP + glutamine => IMP, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Purine metabolism, organism-specific biosystem;
MIM

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