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Panoply™ Human PABPC1 Knockdown Stable Cell Line

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Cat.No.
CSC-DC011221
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
PABPC1
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
PABPC1
Synonyms
PAB1; PABP; PABP1; PABPC2; PABPL1
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
P11940
Chromosome Location
8q22.2-q23
Pathway
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by AUF1 (hnRNP D0), organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem;
Function
nucleotide binding; poly(A) RNA binding; poly(A) RNA binding; protein C-terminus binding; protein binding; translation activator activity;

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