Panoply™ Human NKX2-5 Knockdown Stable Cell Line

Name: Panoply™ Human NKX2-5 Knockdown Stable Cell Line
SKU: CSC-DC010413
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC010413

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC010413
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	NKX2-5
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NKX2-5 NK2 homeobox 5 [ Homo sapiens ]
Gene Symbol	NKX2-5
Synonyms	NKX2-5; NK2 homeobox 5; cardiac specific homeo box , CSX, NK2 transcription factor related, locus 5 (Drosophila) , NKX2E; homeobox protein Nkx-2.5; CSX1; NKX2.5; NKX4 1; tinman paralog (Drosophila); tinman paralog; homeobox protein CSX; cardiac-specific homeobox 1; homeobox protein NK-2 homolog E; NK2 transcription factor related, locus 5; CSX; VSD3; CHNG5; HLHS2; NKX2E; NKX4-1; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536;
Gene ID	1482
Uni Prot ID	P52952
m RNA Refseq	BC025711
Chromosome Location	5q34
Function	DNA binding; chromatin binding; protein binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; contributes_to sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; sequence-specific distal enhancer binding RNA
Pathway	Heart Development, organism-specific biosystem; Regulation of nuclear SMAD2/3 signaling, organism-specific biosystem;
MIM	600584

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