Panoply™ Human NFYB Knockdown Stable Cell Line

Name: Panoply™ Human NFYB Knockdown Stable Cell Line
SKU: CSC-DC010355
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC010355

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC010355
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	NFYB
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NFYB nuclear transcription factor Y, beta [ Homo sapiens ]
Gene Symbol	NFYB
Synonyms	HAP3; CBF-A; CBF-B; NF-YB
Gene Description	nuclear transcription factor Y, beta
Gene ID	4801
Uni Prot ID	P25208
m RNA Refseq	NM_006166.3
Protein Refseq	NP_006157.1
Chromosome Location	12q22-q23
Function	DNA binding; protein binding; protein heterodimerization activity; repressing transcription factor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway	Activation of Chaperone Genes by ATF6-alpha, organism-specific biosystem; Activation of Chaperones by ATF6-alpha, organism-specific biosystem; Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Activation of Genes by ATF4, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Diabetes pathways, organism-specific biosystem;
MIM	189904

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