Panoply™ Human NEUROG3 Knockdown Stable Cell Line

Name: Panoply™ Human NEUROG3 Knockdown Stable Cell Line
SKU: CSC-DC010320
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC010320

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC010320
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	NEUROG3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	NEUROG3 neurogenin 3 [ Homo sapiens ]
Gene Symbol	NEUROG3
Synonyms	NEUROG3; neurogenin 3; neurogenin-3; Atoh5; bHLHa7; Math4B; ngn3; protein atonal homolog 5; class A basic helix-loop-helix protein 7; NGN-3;
GeneID	50674
Uni ProtID	Q9Y4Z2
mRNA Refseq	BC117488
Chromosome Location	10q21.3
Function	DNA binding; double-stranded DNA binding; transcription coactivator activity;
Pathway	Developmental Biology, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem; Maturity onset diabetes of the young, conserved biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; Regulation of beta-cell development, organism-specific biosystem; Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells, organism-specific biosystem; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells, organism-specific biosystem;
MIM	604882

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