Panoply™ Human MYO6 Knockdown Stable Cell Line

Name: Panoply™ Human MYO6 Knockdown Stable Cell Line
SKU: CSC-DC010036
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC010036

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC010036
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	MYO6
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MYO6 myosin VI [ Homo sapiens ]
Gene Symbol	MYO6
Synonyms	DFNA22; DFNB37
GeneID	4646
Uni ProtID	Q9UM54
mRNA Refseq	NM_004999.3
Protein Refseq	NP_004990.3
Chromosome Location	6q13
Function	ADP binding; ATP binding; actin binding; actin filament binding; actin filament binding; calmodulin binding; calmodulin binding; minus-end directed microfilament motor activity; motor activity; protein binding;
Pathway	Gap junction degradation, organism-specific biosystem; Gap junction trafficking, organism-specific biosystem; Gap junction trafficking and regulation, organism-specific biosystem; Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell, organism-specific biosystem;
MIM	600970

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