Panoply™ Human MVK Knockdown Stable Cell Line

Name: Panoply™ Human MVK Knockdown Stable Cell Line
SKU: CSC-DC009951
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC009951

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC009951
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	MVK
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MVK mevalonate kinase [ Homo sapiens ]
Gene Symbol	MVK
Synonyms	MK; LRBP; MVLK
Gene Description	mevalonate kinase (mevalonic aciduria)
GeneID	4598
Uni ProtID	B2RDU6
mRNA Refseq	NM_000431.2
Protein Refseq	NP_000422.1
Chromosome Location	12q24
Function	ATP binding; identical protein binding; mevalonate kinase activity; mevalonate kinase activity; mevalonate kinase activity;
Pathway	Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
MIM	251170

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