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Panoply™ Human MTHFD1L Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC009878

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC009878
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene MTHFD1L
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like [ Homo sapiens ]
Gene Symbol MTHFD1L
Synonyms MTHFD1L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; formyltetrahydrofolate synthetase domain containing 1 , FTHFSDC1; monofunctional C1-tetrahydrofolate synthase, mitochondrial; 10 formyl THF synthetase; DKFZP586G1517; FLJ21145; mitochondrial C1 tetrahydrofolate synthase; monofunctional C1 tetrahydrofolate synthase; mitochondrial; 10-formyl-THF synthetase; formyltetrahydrofolate synthetase domain containing 1; FTHFSDC1; MTC1THFS; dJ292B18.2; RP1-292B18.2; DKFZp586G1517;
Gene ID 25902
Uni Prot ID Q6UB35
m RNA Refseq BC008629
Chromosome Location 6q25.1
Function ATP bindin
Pathway C1-unit interconversion, eukaryotes, organism-specific biosystem; C1-unit interconversion, eukaryotes, conserved biosystem; Metabolic pathways, organism-specific biosystem; One Carbon Metabolism, organism-specific biosystem; One carbon pool by folate, organism-specific biosystem; One carbon pool by folate, conserved biosystem;
MIM 611427
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