Panoply™ Human MMP16 Knockdown Stable Cell Line

Name: Panoply™ Human MMP16 Knockdown Stable Cell Line
SKU: CSC-DC009596
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC009596

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC009596
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	MMP16
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MMP16 matrix metallopeptidase 16 (membrane-inserted) [ Homo sapiens ]
Gene Symbol	MMP16
Synonyms	MMP-X2; C8orf57; MT-MMP2; MT-MMP3; MT3-MMP
Gene Description	matrix metallopeptidase 16 (membrane-inserted)
Gene ID	4325
Uni Prot ID	P51512
m RNA Refseq	NM_005941.4
Protein Refseq	NP_005932.2
Chromosome Location	8q21.3
Function	calcium ion binding; enzyme activator activity; metalloendopeptidase activity; zinc ion binding;
Pathway	Activation of Matrix Metalloproteinases, organism-specific biosystem; Degradation of the extracellular matrix, organism-specific biosystem; Extracellular matrix organization, organism-specific biosystem; Matrix Metalloproteinases, organism-specific biosystem;
MIM	602262

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