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Panoply™ Human MLL Knockdown Stable Cell Line

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Cat.No.
CSC-DC009563
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
MLL
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
MLL
Synonyms
HRX; TRX1; ALL-1; CXXC7; HTRX1; KMT2A; MLL1A; WDSTS; MLL/GAS7; TET1-MLL
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
E9PQG7
Chromosome Location
11q23
Pathway
Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Senescence and Autophagy, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Function
AT DNA binding; histone acetyl-lysine binding; histone methyltransferase activity (H3-K4 specific); histone methyltransferase activity (H3-K4 specific); identical protein binding; protein binding; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; unmethylated CpG binding; zinc ion binding;

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