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Panoply™ Human MCF2 Knockdown Stable Cell Line

Cat.No.
CSC-DC009306
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MCF2
Synonyms
DBL; ARHGEF21
Gene Description
MCF.2 cell line derived transforming sequence
Gene ID
UniProt ID
P10911
mRNA Refseq
Protein Refseq
Chromosome Location
Xq27
Function
Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding;
Pathway
Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Regulation of CDC42 activity, organism-specific biosystem; Regulation of RAC1 activity, organism-specific biosystem;
MIM

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