Panoply™ Human MAPKAPK2 Knockdown Stable Cell Line

Name: Panoply™ Human MAPKAPK2 Knockdown Stable Cell Line
SKU: CSC-DC009211
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC009211

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC009211
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	MAPKAPK2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 [ Homo sapiens ]
Gene Symbol	MAPKAPK2
Synonyms	MK2; MK-2; MAPKAP-K2
GeneID	9261
Uni ProtID	P49137
mRNA Refseq	NM_004759.4
Protein Refseq	NP_004750.1
Chromosome Location	1q32
Function	ATP binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; signal transducer activity;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Arachidonic acid metabolism, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CREB phosphorylation, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; FAS pathway and Stress induction of HSP regulation, organism-specific biosystem;
MIM	602006

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