Panoply™ Human LDLRAP1 Knockdown Stable Cell Line

Name: Panoply™ Human LDLRAP1 Knockdown Stable Cell Line
SKU: CSC-DC008622
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC008622

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC008622
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	LDLRAP1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	LDLRAP1 low density lipoprotein receptor adaptor protein 1 [ Homo sapiens ]
Gene Symbol	LDLRAP1
Synonyms	ARH; ARH1; ARH2; FHCB1; FHCB2
Gene Description	low density lipoprotein receptor adaptor protein 1
Gene ID	26119
Uni Prot ID	B3KR97
m RNA Refseq	NM_015627.2
Protein Refseq	NP_056442.2
Chromosome Location	1p36-p35
Function	AP-2 adaptor complex binding; beta-amyloid binding; clathrin adaptor activity; clathrin binding; low-density lipoprotein particle receptor binding; phosphatidylinositol-4,5-bisphosphate binding; phosphotyrosine binding; protein binding; receptor signaling complex scaffold activity; signaling adaptor activity;
Pathway	Chylomicron-mediated lipid transport, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; LDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem;
MIM	605747

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