Panoply™ Human KMO Knockdown Stable Cell Line

Name: Panoply™ Human KMO Knockdown Stable Cell Line
SKU: CSC-DC008331
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC008331

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC008331
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	KMO
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) [ Homo sapiens ]
Gene Symbol	KMO
Synonyms	KMO; kynurenine 3-monooxygenase (kynurenine 3-hydroxylase); kynurenine 3-monooxygenase; kynurenine 3-hydroxylase; dJ317G22.1;
Gene ID	8564
Uni Prot ID	O15229
m RNA Refseq	BC005297
Chromosome Location	1q42-q44
Function	NAD(P)H oxidase activity; electron carrier activity; flavin adenine dinucleotide binding; kynurenine 3-monooxygenase activity; monooxygenase activity;
Pathway	Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; NAD biosynthesis II (from tryptophan), organism-specific biosystem; NAD biosynthesis II (from tryptophan), conserved biosystem; Selenium Pathway, organism-specific biosystem; Tryptophan catabolism, organism-specific biosystem;
MIM	603538

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