Panoply™ Human KCNQ2 Knockdown Stable Cell Line

Name: Panoply™ Human KCNQ2 Knockdown Stable Cell Line
SKU: CSC-DC008000
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC008000

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC008000
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	KCNQ2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	KCNQ2 potassium voltage-gated channel, KQT-like subfamily, member 2 [ Homo sapiens ]
Gene Symbol	KCNQ2
Synonyms	EBN; BFNC; EBN1; ENB1; BFNS1; EIEE7; HNSPC; KV7.2; KCNA11; KVEBN1
Gene Description	potassium voltage-gated channel, KQT-like subfamily, member 2
GeneID	3785
Uni ProtID	O43526
mRNA Refseq	NM_172107.2
Protein Refseq	NP_742105.1
Chromosome Location	20q13.3
Function	ankyrin binding; potassium channel activity; voltage-gated potassium channel activity;
Pathway	Axon guidance, organism-specific biosystem; Cholinergic synapse, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem;
MIM	602235

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