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Panoply™ Human ITK Knockdown Stable Cell Line

Cat.No.
CSC-DC007819
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ITK
Synonyms
EMT; LYK; PSCTK2
Gene Description
IL2-inducible T-cell kinase
Gene ID
UniProt ID
Q08881
mRNA Refseq
Protein Refseq
Chromosome Location
5q31-q32
Function
ATP binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; phospholipid binding; protein binding;
Pathway
Adaptive Immune System, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; Fc-epsilon receptor I signaling in mast cells, organism-specific biosystem; Generation of second messenger molecules, organism-specific biosystem;
MIM

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