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Panoply™ Human ISL1 Knockdown Stable Cell Line

Cat.No.
CSC-DC007765
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ISL1
Synonyms
Isl-1; ISLET1
Gene Description
ISL1 transcription factor, LIM/homeodomain, (islet-1)
Gene ID
UniProt ID
P61371
mRNA Refseq
Protein Refseq
Chromosome Location
5q11.1
Function
RNA polymerase II activating transcription factor binding; RNA polymerase II transcription coactivator activity; bHLH transcription factor binding; enhancer sequence-specific DNA binding; enhancer sequence-specific DNA binding; estrogen receptor binding; ligand-dependent nuclear receptor binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;
Pathway
Heart Development, organism-specific biosystem; Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Neural Crest Differentiation, organism-specific biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP), organism-specific biosystem;
MIM

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