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Panoply™ Human IKBKB Knockdown Stable Cell Line

Cat.No.
CSC-DC007520
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
IKBKB
Synonyms
IKK2; IKKB; NFKBIKB; IKK-beta
Gene Description
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene ID
UniProt ID
O14920
mRNA Refseq
Protein Refseq
Chromosome Location
8p11.2
Function
ATP binding; IkappaB kinase activity; protein binding; protein heterodimerization activity; protein kinase activity; protein kinase binding; protein serine/threonine kinase activity;
Pathway
Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem;
MIM

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