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Panoply™ Human HS3ST5 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC007263

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC007263
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene HS3ST5
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name HS3ST5 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 [ Homo sapiens ]
Gene Symbol HS3ST5
Synonyms 3OST5; 3-OST-5; HS3OST5; NBLA04021
Gene ID 222537
Uni Prot ID Q8IZT8
m RNA Refseq NM_153612.3
Protein Refseq NP_705840.2
Chromosome Location 6q21
Function 3-phosphoadenosine 5-phosphosulfate binding; [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity; protein binding;
Pathway Disease, organism-specific biosystem; Glycosaminoglycan biosynthesis - heparan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - heparan sulfate, conserved biosystem; Glycosaminoglycan metabolism, organism-specific biosystem; HS-GAG biosynthesis, organism-specific biosystem; Heparan sulfate/heparin (HS-GAG) metabolism, organism-specific biosystem; MPS I - Hurler syndrome, organism-specific biosystem;
MIM 609407
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