Panoply™ Human HEYL Knockdown Stable Cell Line

Name: Panoply™ Human HEYL Knockdown Stable Cell Line
SKU: CSC-DC006963
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006963

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006963
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	HEYL
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	HEYL hairy/enhancer-of-split related with YRPW motif-like [ Homo sapiens ]
Gene Symbol	HEYL
Synonyms	HEY3; HRT3; bHLHb33
Gene Description	hairy/enhancer-of-split related with YRPW motif-like
GeneID	26508
Uni ProtID	Q9NQ87
mRNA Refseq	NM_014571.3
Protein Refseq	NP_055386.1
Chromosome Location	1p34.3
Function	AF-1 domain binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription corepressor activity; microsatellite binding; protein binding; protein binding transcription factor activity; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; transcription factor binding;
Pathway	NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;
MIM	609034

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