Panoply™ Human HCRT Knockdown Stable Cell Line

Name: Panoply™ Human HCRT Knockdown Stable Cell Line
SKU: CSC-DC006880
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006880

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006880
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	HCRT
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	HCRT hypocretin (orexin) neuropeptide precursor [ Homo sapiens ]
Gene Symbol	HCRT
Synonyms	OX; PPOX; NRCLP1
Gene Description	hypocretin (orexin) neuropeptide precursor
Gene ID	15171
Uni Prot ID	O43612
m RNA Refseq	NM_001524.1
Protein Refseq	NP_001515.1
Chromosome Location	17q21
Function	neuropeptide hormone activity; type 1 hypocretin receptor binding; type 2 hypocretin receptor binding;
Pathway	Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem; Orexin and neuropeptides FF and QRFP bind to their respective receptors, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem;
MIM	602358

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