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Panoply™ Human HCRT Knockdown Stable Cell Line

Cat.No.
CSC-DC006880
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
HCRT
Synonyms
OX; PPOX; NRCLP1
Gene Description
hypocretin (orexin) neuropeptide precursor
Gene ID
UniProt ID
O43612
mRNA Refseq
Protein Refseq
Chromosome Location
17q21
Function
neuropeptide hormone activity; type 1 hypocretin receptor binding; type 2 hypocretin receptor binding;
Pathway
Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem; Orexin and neuropeptides FF and QRFP bind to their respective receptors, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem;
MIM

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