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Panoply™ Human H2AFX Knockdown Stable Cell Line

Cat.No.
CSC-DC006808
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
H2AFX
Synonyms
H2AX; H2A.X; H2A/X
Gene Description
H2A histone family, member X
Gene ID
UniProt ID
P16104
mRNA Refseq
Protein Refseq
Chromosome Location
11q23.3
Function
DNA binding; damaged DNA binding; enzyme binding; histone binding; protein binding; protein heterodimerization activity;
Pathway
ATM mediated phosphorylation of repair proteins, organism-specific biosystem; ATM mediated response to DNA double-strand break, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Amyloids, organism-specific biosystem; Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; Cell Cycle, organism-specific biosystem;
MIM

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