Panoply™ Human GTF2B Knockdown Stable Cell Line

Name: Panoply™ Human GTF2B Knockdown Stable Cell Line
SKU: CSC-DC006734
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006734

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006734
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GTF2B
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GTF2B general transcription factor IIB [ Homo sapiens ]
Gene Symbol	GTF2B
Synonyms	GTF2B; general transcription factor IIB; transcription initiation factor IIB; TFIIB; S300-II; general transcription factor TFIIB; RNA polymerase II transcription factor IIB; TF2B;
Gene ID	2959
Uni Prot ID	Q00403
m RNA Refseq	BC020597
Chromosome Location	1p22-p21
Function	DNA binding; metal ion binding; protein binding; thyroid hormone receptor binding; transcription factor binding; translation initiation factor activity; zinc ion binding;
Pathway	Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; Disease, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Gene Expression, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem;
MIM	189963

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