Panoply™ Human GRIA2 Knockdown Stable Cell Line

Name: Panoply™ Human GRIA2 Knockdown Stable Cell Line
SKU: CSC-DC006647
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006647

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006647
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GRIA2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GRIA2 glutamate receptor, ionotropic, AMPA 2 [ Homo sapiens ]
Gene Symbol	GRIA2
Synonyms	GLUR2; GLURB; GluA2; HBGR2; GluR-K2
Gene Description	glutamate receptor, ionotropic, AMPA 2
Gene ID	14800
Uni Prot ID	I6L997
m RNA Refseq	NM_001083619.1
Protein Refseq	NP_001077088.1
Chromosome Location	4q32.1
Function	alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; extracellular-glutamate-gated ion channel activity; glutamate receptor activity; ionotropic glutamate receptor activity; kainate selective glutamate receptor activity; protein kinase binding;
Pathway	Activation of AMPA receptors, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Cocaine addiction, organism-specific biosystem;
MIM	138247

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