Panoply™ Human GNB2L1 Knockdown Stable Cell Line

Name: Panoply™ Human GNB2L1 Knockdown Stable Cell Line
SKU: CSC-DC006397
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006397

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006397
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GNB2L1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [ Homo sapiens ]
Gene Symbol	GNB2L1
Synonyms	H12.3; HLC-7; PIG21; RACK1; Gnb2-rs1
Gene Description	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GeneID	10399
Uni ProtID	E9KL35
mRNA Refseq	NM_006098.4
Protein Refseq	NP_006089.1
Chromosome Location	5q35.3
Function	SH2 domain binding; ion channel inhibitor activity; protein binding; protein kinase C binding; protein phosphatase binding; protein tyrosine kinase inhibitor activity; receptor binding; receptor tyrosine kinase binding;
Pathway	CXCR4-mediated signaling events, organism-specific biosystem; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; IL-2 Signaling Pathway, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem; Measles, organism-specific biosystem; Measles, conserved biosystem;
MIM	176981

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