Panoply™ Human GMDS Knockdown Stable Cell Line

Name: Panoply™ Human GMDS Knockdown Stable Cell Line
SKU: CSC-DC006364
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006364

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006364
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GMDS
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GMDS GDP-mannose 4,6-dehydratase [ Homo sapiens ]
Gene Symbol	GMDS
Synonyms	GMDS; GDP-mannose 4,6-dehydratase; GDP-mannose 4,6 dehydratase; GMD; SDR3E1; short chain dehydrogenase/reductase family 3E; member 1; GDP-D-mannose dehydratase; short chain dehydrogenase/reductase family 3E, member 1;
GeneID	2762
Uni ProtID	O60547
mRNA Refseq	BC000117
Chromosome Location	6p25
Function	GDP-mannose 4,6-dehydratase activity; GDP-mannose 4,6-dehydratase activity; NADP+ binding; coenzyme binding; lyase activity; nucleotide binding;
Pathway	Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; GDP-L-fucose biosynthesis I (from GDP-D-mannose), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; colanic acid building blocks biosynthesis, organism-specific biosystem;
MIM	602884

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