Panoply™ Human GGPS1 Knockdown Stable Cell Line

Name: Panoply™ Human GGPS1 Knockdown Stable Cell Line
SKU: CSC-DC006236
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC006236

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC006236
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	GGPS1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	GGPS1 geranylgeranyl diphosphate synthase 1 [ Homo sapiens ]
Gene Symbol	GGPS1
Synonyms	GGPPS; GGPPS1
Gene Description	geranylgeranyl diphosphate synthase 1
GeneID	9453
Uni ProtID	O95749
mRNA Refseq	NM_001037277.1
Protein Refseq	NP_001032354.1
Chromosome Location	1q43
Function	dimethylallyltranstransferase activity; farnesyltranstransferase activity; geranyltranstransferase activity; metal ion binding;
Pathway	Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Regulation of Cholesterol Biosynthesis by SREBP (SREBF), organism-specific biosystem; Terpenoid backbone biosynthesis, organism-specific biosystem; Terpenoid backbone biosynthesis, conserved biosystem;
MIM	606982

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