Panoply™ Human FRAT1 Knockdown Stable Cell Line

Name: Panoply™ Human FRAT1 Knockdown Stable Cell Line
SKU: CSC-DC005892
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC005892

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC005892
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	FRAT1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	FRAT1 frequently rearranged in advanced T-cell lymphomas [ Homo sapiens ]
Gene Symbol	FRAT1
GeneID	10023
Uni ProtID	Q92837
mRNA Refseq	NM_005479.3
Protein Refseq	NP_005470.2
Chromosome Location	10q24.1
Pathway	Beta-catenin phosphorylation cascade, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Degradation of beta-catenin by the destruction complex, organism-specific biosystem; Presenilin action in Notch and Wnt signaling, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Wnt, organism-specific biosystem; Wnt Signaling Pathway, organism-specific biosystem;
MIM	602503

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