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Panoply™ Human FOXP3 Knockdown Stable Cell Line

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Cat.No.
CSC-DC005878
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
FOXP3
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
FOXP3
Synonyms
JM2; AIID; IPEX; PIDX; XPID; DIETER
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q9BZS1
Chromosome Location
Xp11.23
Pathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; IL2 signaling events mediated by STAT5, organism-specific biosystem;
Function
DNA binding, bending; NF-kappaB binding; NFAT protein binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; chromatin binding; double-stranded DNA binding; histone acetyltransferase binding; histone deacetylase binding; protein binding; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription corepressor activity; zinc ion binding;

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