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Panoply™ Human FOXO4 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC005875

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC005875
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene FOXO4
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name FOXO4 forkhead box O4 [ Homo sapiens ]
Gene Symbol FOXO4
Synonyms FOXO4; forkhead box O4; MLLT7, myeloid/lymphoid or mixed lineage leukemia (trithorax (Drosophila) homolog); translocated to, 7 , myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila); translocated to, 7; forkhead box protein O4; AFX1; fork head domain transcription factor AFX1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7; AFX; MLLT7; MGC120490;
Gene ID 4303
Uni Prot ID P98177
m RNA Refseq BC106761
Chromosome Location Xq13.1
Function DNA binding; DNA binding, bending; double-stranded DNA binding; enzyme bi
Pathway AKT phosphorylates targets in the nucleus, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; Disease, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; Downstream signaling of activated FGFR, organism-specific biosystem;
MIM 300033
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