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Panoply™ Human FOXO1 Knockdown Stable Cell Line

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Cat.No.
CSC-DC005873
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
FOXO1
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
FOXO1
Synonyms
FKH1; FKHR; FOXO1A
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q12778
Chromosome Location
13q14.1
Pathway
AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem;
Function
DNA binding, bending; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; chromatin binding; double-stranded DNA binding; protein binding; protein kinase binding; protein phosphatase 2A binding; sequence-specific DNA binding; transcription factor binding;

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