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Panoply™ Human FOXO1 Knockdown Stable Cell Line

Cat.No.
CSC-DC005873
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
FOXO1A
Synonyms
FKH1; FKHR; FOXO1A
Gene Description
forkhead box O1A
Gene ID
UniProt ID
Q12778
mRNA Refseq
Protein Refseq
Chromosome Location
13q14.1
Function
DNA binding, bending; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; chromatin binding; double-stranded DNA binding; protein binding; protein kinase binding; protein phosphatase 2A binding; sequence-specific DNA binding; transcription factor binding;
Pathway
AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem;
MIM

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