Panoply™ Human FOXH1 Knockdown Stable Cell Line

Name: Panoply™ Human FOXH1 Knockdown Stable Cell Line
SKU: CSC-DC005857
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC005857

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC005857
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	FOXH1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	FOXH1 forkhead box H1 [ Homo sapiens ]
Gene Symbol	FOXH1
Synonyms	FAST1; FAST-1
GeneID	8928
Uni ProtID	O75593
mRNA Refseq	NM_003923.2
Protein Refseq	NP_003914.1
Chromosome Location	8q24.3
Function	contributes_to DNA binding; DNA binding, bending; R-SMAD binding; R-SMAD binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription cofactor activity; RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; androgen receptor binding; co-SMAD binding; double-stranded DNA binding; protein binding; protein domain specific binding; sequence-specific DNA binding; contributes_to sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding;
Pathway	Developmental Biology, organism-specific biosystem; Heart Development, organism-specific biosystem; Regulation of nuclear SMAD2/3 signaling, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; TGF Beta Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
MIM	603621

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