Panoply™ Human FOXA2 Knockdown Stable Cell Line

Name: Panoply™ Human FOXA2 Knockdown Stable Cell Line
SKU: CSC-DC005836
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC005836

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC005836
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	FOXA2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	FOXA2 forkhead box A2 [ Homo sapiens ]
Gene Symbol	FOXA2
Synonyms	HNF3B; TCF3B
Gene ID	3170
Uni Prot ID	B0ZTD4
m RNA Refseq	NM_021784.4
Protein Refseq	NP_068556.2
Chromosome Location	20p11
Function	DNA binding; DNA binding, bending; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; SMAD binding; double-stranded DNA binding; protein domain specific binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding;
Pathway	Developmental Biology, organism-specific biosystem; FOXA transcription factor networks, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Heart Development, organism-specific biosystem; Hedgehog signaling events mediated by Gli proteins, organism-specific biosystem; Maturity onset diabetes of the young, organism-specific biosystem;
MIM	600288

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