Panoply™ Human FOSL1 Knockdown Stable Cell Line

Name: Panoply™ Human FOSL1 Knockdown Stable Cell Line
SKU: CSC-DC005833
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC005833

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC005833
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	FOSL1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	FOSL1 FOS-like antigen 1 [ Homo sapiens ]
Gene Symbol	FOSL1
Synonyms	FRA; FRA1; fra-1
Gene Description	FOS-like antigen 1
Gene ID	8061
Uni Prot ID	P15407
m RNA Refseq	NM_005438.3
Protein Refseq	NP_005429.1
Chromosome Location	11q13
Function	protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway	Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; Downstream signaling in naive CD8+ T cells, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Osteoclast differentiation, organism-specific biosystem;
MIM	136515

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