Panoply™ Human FLNA Knockdown Stable Cell Line

Name: Panoply™ Human FLNA Knockdown Stable Cell Line
SKU: CSC-DC005779
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC005779

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC005779
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	FLNA
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	FLNA filamin A, alpha [ Homo sapiens ]
Gene Symbol	FLNA
Synonyms	FLN; FMD; MNS; OPD; ABPX; CVD1; FLN1; NHBP; OPD1; OPD2; XLVD; XMVD; FLN-A; ABP-280
Gene Description	filamin A, alpha (actin binding protein 280)
GeneID	2316
Uni ProtID	P21333
mRNA Refseq	NM_001456.3
Protein Refseq	NP_001447.2
Chromosome Location	Xq28
Function	Fc-gamma receptor I complex binding; Rac GTPase binding; Ral GTPase binding; Rho GTPase binding; actin filament binding; glycoprotein binding; protein binding; protein homodimerization activity; signal transducer activity; small GTPase binding; transcription factor binding;
Pathway	Androgen Receptor Signaling Pathway, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-extracellular matrix interactions, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
MIM	300017

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