Panoply™ Human EP300 Knockdown Stable Cell Line

Name: Panoply™ Human EP300 Knockdown Stable Cell Line
SKU: CSC-DC004966
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004966

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004966
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	EP300
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	EP300 E1A binding protein p300 [ Homo sapiens ]
Gene Symbol	EP300
Synonyms	p300; KAT3B; RSTS2
GeneID	2033
Uni ProtID	Q09472
mRNA Refseq	NM_001429.3
Protein Refseq	NP_001420.2
Chromosome Location	22q13.2
Function	DNA binding; NF-kappaB binding; RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; acetyltransferase activity; activating transcription factor binding; androgen receptor binding; antigen binding; beta-catenin binding; chromatin DNA binding; chromatin binding; core promoter binding; glucocorticoid receptor binding; histone acetyltransferase activity; lysine N-acetyltransferase activity; mitogen-activated protein kinase binding; p53 binding; peroxisome proliferator activated receptor binding; protein binding; protein complex binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; contributes_to transcription coactivator activity; transcription factor binding; transferase activity, transferring acyl groups; zinc ion binding;
Pathway	ATF-2 transcription factor network, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Cell cycle, organism-specific biosystem;
MIM	602700

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