Panoply™ Human EIF2S2 Knockdown Stable Cell Line

Name: Panoply™ Human EIF2S2 Knockdown Stable Cell Line
SKU: CSC-DC004809
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004809

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004809
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	EIF2S2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa [ Homo sapiens ]
Gene Symbol	EIF2S2
Synonyms	EIF2; EIF2B; PPP1R67; EIF2beta; eIF-2-beta
Gene Description	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
Gene ID	8894
Uni Prot ID	P20042
m RNA Refseq	NM_003908.3
Protein Refseq	NP_003899.2
Chromosome Location	20q11.2
Function	RNA binding; metal ion binding; protein binding; translation factor activity, nucleic acid binding; translation initiation factor activity;
Pathway	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem; Gene Expression, organism-specific biosystem; L13a-mediated translational silencing of Ceruloplasmin expression, organism-specific biosystem;
MIM	603908

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