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Panoply™ Human EGLN2 Knockdown Stable Cell Line

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Cat.No.
CSC-DC004774
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
EGLN2
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
EGLN2
Synonyms
EIT6; PHD1; HPH-1; HPH-3; HIFPH1; HIF-PH1
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q96KS0
Chromosome Location
19q13.2
Pathway
Cellular response to hypoxia, organism-specific biosystem; Cellular responses to stress, organism-specific biosystem; HIF-1 signaling pathway, organism-specific biosystem; HIF-2-alpha transcription factor network, organism-specific biosystem; Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha, organism-specific biosystem; Pathways in cancer, organism-specific biosystem; Regulation of Hypoxia-inducible Factor (HIF) by Oxygen, organism-specific biosystem;
Function
L-ascorbic acid binding; ferrous iron binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; oxygen sensor activity; peptidyl-proline 4-dioxygenase activity; protein binding;

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