Panoply™ Human ECT2 Knockdown Stable Cell Line

Name: Panoply™ Human ECT2 Knockdown Stable Cell Line
SKU: CSC-DC004703
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004703

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004703
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ECT2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ECT2 epithelial cell transforming sequence 2 oncogene [ Homo sapiens ]
Gene Symbol	ECT2
Synonyms	ARHGEF31
Gene ID	1894
Uni Prot ID	Q9H8V3
m RNA Refseq	NM_001258315.1
Protein Refseq	NP_001245244.1
Chromosome Location	3q26.1-q26.2
Function	GTPase activator activity; Rho GTPase binding; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding; protein homodimerization activity; signal transducer activity;
Pathway	Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; PLK1 signaling events, organism-specific biosystem; Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem;
MIM	600586

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