Panoply™ Human DTL Knockdown Stable Cell Line

Name: Panoply™ Human DTL Knockdown Stable Cell Line
SKU: CSC-DC004578
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004578

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC004578
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	DTL
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) [ Homo sapiens ]
Gene Symbol	DTL
Synonyms	DTL; denticleless E3 ubiquitin protein ligase homolog (Drosophila); denticleless homolog (Drosophila); denticleless protein homolog; DCAF2; DDB1 and CUL4 associated factor 2; L2DTL; RA regulated nuclear matrix associated protein; RAMP; denticleless homolog; DDB1- and CUL4-associated factor 2; lethal denticleless protein homolog; RA-regulated nuclear matrix-associated protein; retinoic acid-regulated nuclear matrix-associated protein; CDT2;
GeneID	51514
Uni ProtID	Q9NZJ0
mRNA Refseq	BC033540
Chromosome Location	1q32
Function	protein binding; contributes_to ubiquitin-protein ligase activity;
MIM	610617

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