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Panoply™ Human DOT1L Knockdown Stable Cell Line

Cat.No.
CSC-DC004496
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
DOT1L
Synonyms
DOT1; KMT4
Gene Description
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
Gene ID
UniProt ID
Q8TEK3
mRNA Refseq
Protein Refseq
Chromosome Location
19p13.3
Function
DNA binding; histone-lysine N-methyltransferase activity; protein binding; transcription factor binding;
Pathway
Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
MIM

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