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Panoply™ Human DOT1L Knockdown Stable Cell Line

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Cat.No.
CSC-DC004496
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
DOT1L
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
DOT1L
Synonyms
DOT1; KMT4
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q8TEK3
Chromosome Location
19p13.3
Pathway
Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;
Function
DNA binding; histone-lysine N-methyltransferase activity; protein binding; transcription factor binding;

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