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Panoply™ Human DIS3 Knockdown Stable Cell Line

Cat.No.
CSC-DC004319
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
DIS3
Synonyms
RRP44; dis3p; EXOSC11; KIAA1008; bA555G22.1; RP11-342J4.3
Gene ID
UniProt ID
Q9Y2L1
mRNA Refseq
Protein Refseq
Chromosome Location
13q22.1
Function
3-5-exoribonuclease activity; RNA binding; endonuclease activity; guanyl-nucleotide exchange factor activity; protein binding;
Pathway
Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
MIM

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