Panoply™ Human DHX58 Knockdown Stable Cell Line

Name: Panoply™ Human DHX58 Knockdown Stable Cell Line
SKU: CSC-DC004297
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004297

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004297
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	DHX58
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 [ Homo sapiens ]
Gene Symbol	DHX58
Synonyms	DHX58; DEXH (Asp-Glu-X-His) box polypeptide 58; probable ATP-dependent RNA helicase DHX58; D11LGP2; LGP2; RNA helicase LGP2; RLR; protein D11Lgp2 homolog; RIG-I-like receptor LGP2; ortholog of mouse D11lgp2; probable ATP-dependent helicase LGP2; D11lgp2e;
Gene ID	79132
Uni Prot ID	Q96C10
m RNA Refseq	BC014949
Chromosome Location	17q21.2
Function	ATP binding; DNA binding; RNA binding; helicase activity; hydrolase activity, acting on acid anhydrides; metal ion binding; nucleotide binding; protein binding; zinc ion binding;
Pathway	Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; RIG-I-like receptor signaling pathway, organism-specific biosystem; RIG-I-like receptor signaling pathway, conserved biosystem; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem;
MIM	608588

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