Panoply™ Human DDB2 Knockdown Stable Cell Line

Name: Panoply™ Human DDB2 Knockdown Stable Cell Line
SKU: CSC-DC004117
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004117

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004117
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	DDB2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DDB2 damage-specific DNA binding protein 2, 48kDa [ Homo sapiens ]
Gene Symbol	DDB2
Synonyms	DDBB; UV-DDB2
Gene Description	damage-specific DNA binding protein 2, 48kDa
Gene ID	1643
Uni Prot ID	Q92466
m RNA Refseq	NM_000107.2
Protein Refseq	NP_000098.1
Chromosome Location	11p12-p11
Function	DNA binding; damaged DNA binding; protein binding; contributes_to ubiquitin-protein ligase activity;
Pathway	Cul4-DDB1-DDB2 complex, organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA damage response, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Formation of incision complex in GG-NER, organism-specific biosystem; Global Genomic NER (GG-NER), organism-specific biosystem;
MIM	600811

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