Panoply™ Human DCLRE1C Knockdown Stable Cell Line

Name: Panoply™ Human DCLRE1C Knockdown Stable Cell Line
SKU: CSC-DC004089
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004089

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004089
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	DCLRE1C
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DCLRE1C DNA cross-link repair 1C [ Homo sapiens ]
Gene Symbol	DCLRE1C
Synonyms	SCIDA; SNM1C; A-SCID; hSNM1C; RS-SCID; DCLREC1C
Gene Description	DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae)
GeneID	64421
Uni ProtID	Q96SD1
mRNA Refseq	NM_001033855.1
Protein Refseq	NP_001029027.1
Chromosome Location	10p13
Function	5-3 exonuclease activity; single-stranded DNA specific endodeoxyribonuclease activity;
Pathway	Non-homologous end-joining, organism-specific biosystem; Non-homologous end-joining, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem;
MIM	605988

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