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Panoply™ Human CYP46A1 Knockdown Stable Cell Line

Cat.No.
CSC-DC003974
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CYP46A1
Synonyms
CP46; CYP46
Gene Description
cytochrome P450, family 46, subfamily A, polypeptide 1
Gene ID
UniProt ID
Q9Y6A2
mRNA Refseq
Protein Refseq
Chromosome Location
14q32.1
Function
cholesterol 24-hydroxylase activity; electron carrier activity; heme binding; iron ion binding; steroid hydroxylase activity;
Pathway
Bile acid and bile salt metabolism, organism-specific biosystem; Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem; Endogenous sterols, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Phase 1 - Functionalization of compounds, organism-specific biosystem;
MIM

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